Lansoprazole Worsens Asthma Control in Poor Metabolizers: Is Nitric Oxide Involved?
نویسندگان
چکیده
منابع مشابه
Nasal nitric oxide is a marker of poor asthma control.
Asthma control, evaluated by symptoms, exacerbations rate and lung function may be greatly influenced by comorbidities, particularly chronic rhinosinusitis (CRS). Measurement of nasal nitric oxide (nNO) is a simple way to assess the severity of CRS. We aimed to analyze the relationship between asthma control and nasal NO. All patients with moderate-to-severe asthma on regular follow-up at our O...
متن کاملExhaled nitric oxide is increased in asthma.
and the lack of a response to hyperventilation, may not relate to asthma so much as they relate to disease severity or patient age. Finally, changes in responsiveness induced by allergen stimulation are not related to baseline AHR. This suggests that chronic persistent AHR may have underlying mechanisms that differ from those responsible for short-term changes in AHR induced by inflammation. Ou...
متن کاملIs Nitric Oxide a Hormone?
Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production i...
متن کاملNitric Oxide in Asthma
Nitrogen monoxide, more commonly called nitric oxide or simply NO, is a fascinating free radical molecule, which participates in a broad range of important physiologic processes, including vasodilation, neurotransmission, and host defense. NO is generated from L -arginine by the enzyme nitric oxide synthase (NOS), of which there are three known isoforms. Types I and III NOS, found predominantly...
متن کاملNitric oxide and asthma.
Since nitric oxide (NO) was first described as endothelium derived relaxing factor (EDRF),I there has been compelling evidence that NO is involved in very many biological processes.2-9 It has at least four roles in the lungs.3 These are as a pulmonary vasodilator, bronchodilator, non-adrenergic non-cholinergic transmitter, and inflammatory mediator. There are three types of NO synthase, the enz...
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ژورنال
عنوان ژورنال: Annals of the American Thoracic Society
سال: 2015
ISSN: 2329-6933,2325-6621
DOI: 10.1513/annalsats.201504-238le